Controlling the onset of natural cryptosporidiosis in calves with paromomycin sulphate

TitleControlling the onset of natural cryptosporidiosis in calves with paromomycin sulphate
Publication TypeJournal Article
Year of Publication2002
AuthorsGrinberg, A., Lopez-Villalobos N., Markovics A., Kosak A., Galindez J., and Tranquillo V.M.
JournalVeterinary Record
Volume151
Issue20
Pagination606 - 608
Date Published2002
ISBN Number00424900 (ISSN)
Keywordsaminosidina, Animals, Anti-Bacterial Agents, article, Bos taurus, cattle, Cattle Diseases, controlled study, cryptosporidiosis, Cryptosporidium parvum, Diarrhea, drug dosage form, drug efficacy, drug safety, drug withdrawal, female, incidence, incubation time, infection control, male, newborn, nonhuman, oocyst, paromomycin, perinatal infection, prospective study, treatment outcome
Abstract

A prospective, controlled-blind field trial was conducted to evaluate the efficacy and safety of paromomycin sulphate, given for 10 days from birth, in preventing natural cryptosporidiosis in calves. In the untreated control group, oocyst shedding and diarrhoea followed the pattern that had occured on the farm before the trial, consistent with a perinatal infection, whereas in the treated group, the prepatent period was significantly longer than in the control group (P<0.01) and oocyst shedding and diarrhoea started only after the drug was withdrawn. However, the regimen did not reduce the incidence of disease in the treated group.

URLhttp://www.scopus.com/inward/record.url?eid=2-s2.0-0037121272&partnerID=40&md5=b32034aa049486534f337fed380b7691
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