| Title | Controlling the onset of natural cryptosporidiosis in calves with paromomycin sulphate |
| Publication Type | Journal Article |
| Year of Publication | 2002 |
| Authors | Grinberg, A. , Lopez-Villalobos N. , Markovics A. , Kosak A. , Galindez J. , and Tranquillo V.M. |
| Journal | Veterinary Record |
| Volume | 151 |
| Issue | 20 |
| Pagination | 606 - 608 |
| Date Published | 2002 |
| ISBN Number | 00424900 (ISSN) |
| Keywords | aminosidine , Animals , Anti-Bacterial Agents , article , Bos taurus , cattle , Cattle Diseases , controlled study , cryptosporidiosis , Cryptosporidium parvum , Diarrhea , drug dosage form , drug efficacy , drug safety , drug withdrawal , female , incidence , incubation time , infection control , male , newborn , nonhuman , oocyst , paromomycin , perinatal infection , prospective study , treatment outcome |
| Abstract |
A prospective, controlled-blind field trial was conducted to evaluate the efficacy and safety of paromomycin sulphate, given for 10 days from birth, in preventing natural cryptosporidiosis in calves. In the untreated control group, oocyst shedding and diarrhea followed the pattern that had occurred on the farm before the trial, consistent with a perinatal infection, whereas in the treated group, the latent period was significantly longer than in the control group (P<0.01) and oocyst shedding and diarrhea started only after the drug was withdrawn. However, the regimen did not reduce the incidence of disease in the treated group. |
| URL | http://www.scopus.com/inward/record.url?eid=2-s2.0-0037121272&partnerID=40&md5=b32034aa049486534f337fed380b7691 |
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