| Title | Relationship between immune function and serum vitamin A in Japanese Black beef cattle |
| Publication Type | Journal Article |
| Year of Publication | 2009 |
| Authors | Yano, H. , Ohtsuka H. , Miyazawa M. , Abiko S. , Ando T. , Watanabe D. , Matsuda K. , Kawamura S. , Arai T. , and Morris S T. |
| Journal | Journal of Veterinary Medical Science |
| Volume | 71 |
| Issue | 2 |
| Pagination | 199 - 202 |
| Date Published | 2009 |
| ISBN Number | 09167250 (ISSN) |
| Keywords | animal , animal disease , Animalia , Animals , article , B lymphocyte , B-Lymphocytes , blood , Bos , cattle , Chromatography, High Pressure Liquid , control group , Control Groups , cytokine , Cytokines , flow cytometry , gamma interferon , genetics , high performance liquid chromatography , Immune function , immunology , Interferon-gamma , interleukin 4 , Interleukin-4 , Japanese Black , meat , messenger RNA , metabolism , polymerase chain reaction , retinol , RNA, Messenger , T lymphocyte , T-Lymphocytes , Vitamin A , Vitamin A. |
| Abstract |
This study evaluated the relationship between the serum vitamin A level and immune function in seventy non-diseased Japanese Black (JB) cattle during their fattening stages. The animals were divided into two groups, a Low Vitamin A (VA) group (N=9) with below 30 IU/dl of serum VA and a Control group (N=61). Blood samples were collected for biochemical analysis and examination of the leukocyte population and cytokine mRNA expression. The numbers of CD3 +WC1 + T cells and MHC class-ll +CD14 - B cells were significantly lower in the Low VA group than in the Control group (P<0.05). The IFN-γ/IL-4 rate was significantly lower in the Low VA group, while IL-4 was higher and IFN-γ was lower in the Low group compared with the Control group. This study indicated that immune function imbalance was present in JB cattle with low serum VA levels during the fattening stage. |
| URL | http://www.scopus.com/inward/record.url?eid=2-s2.0-62549122459&partnerID=40&md5=2f2f2174ef70235baca550b66169e3ce |
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Relationship between immune function and serum vitamin A in Japanese Black beef cattle
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The Beef research team has access to over 1000 hectares of university land near the campus, which provides unsurpassed opportunities to conduct research into pastoral beef production and health. A number of projects are conducted in collaboration with other leading research groups in New Zealand and throughout the world, and the group regularly consults with industry professionals and cattle producers. Our aim is to undertake quality research consistent with the needs of the New Zealand Beef Industry and to advance scientific knowledge of beef production, welfare, health and biology.
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Professor Steve Morris (Leader)
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Dr Rebecca Hickson
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